Hyaluronic Acid

A Moisture-Binding Molecule That Supports Surface Hydration and Skin Softness

Hyaluronic acid in Ascellos™ supports visible skin hydration, elasticity, and comfort through a non-cellular, cosmetic-use format. It binds moisture at the skin surface, helping improve suppleness, smoothness, and tolerance following procedures. This acellular formulation aligns with FDA cosmetic guidelines and complements recovery-focused regimens without systemic effects or therapeutic claims.

What Is Hyaluronic Acid?

Hyaluronic acid is a naturally occurring glycosaminoglycan found in the skin, joints, and connective tissue that binds large amounts of water to maintain hydration and tissue volume. In Ascellos™, it is included as a purified, non-animal-derived topical component that improves surface moisture without injections or systemic absorption. Its cosmetic use supports visible hydration and softening in post-procedure recovery.

How Does Hyaluronic Acid Work?

Hyaluronic acid improves post-procedure skin appearance by enhancing hydration, comfort, and tissue flexibility through non-cellular cosmetic action.

  • Moisture Attraction and Retention:As a humectant, hyaluronic acid draws water from the environment and deeper dermal layers to the skin surface, increasing hydration and visible plumpness.
  • Skin Plumping and Texture Refinement: The added moisture expands the extracellular space, smoothing surface lines and making skin appear fuller and more even in tone.
  • Elasticity Maintenance: By supporting hydration between collagen and elastin fibers, hyaluronic acid helps preserve stretch and flexibility in recovering skin.
  • Structural Support in the ECM: It interacts with proteins in the extracellular matrix to stabilize tissue structure and maintain firmness after cosmetic stress.
  • Wound Healing Assistance: Hyaluronic acid plays a role in post-procedure recovery by promoting keratinocyte migration and modulating inflammation to support faster surface repair.

These combined mechanisms make hyaluronic acid an effective cosmetic option for improving comfort, tone, and elasticity after aesthetic procedures.

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What Does Hyaluronic Acid Do?

Hyaluronic acid supports cosmetic recovery by enhancing moisture retention, improving skin suppleness, and promoting visible comfort after procedures.

  • Deep hydration and moisture retention: Hyaluronic acid draws water to the skin’s surface, visibly plumping dehydrated areas and reducing tightness during recovery.
  • Elasticity and firmness improvement: It enhances moisture within the extracellular matrix, helping skin remain flexible, firm, and more resistant to sagging
  • Smoother surface texture: Increased hydration softens rough patches, reduces fine lines, and promotes a more even skin texture without irritation.
  • Wound healing support: It aids re-epithelialization by supporting skin cell migration and moderating inflammation after resurfacing procedures.
  • Redness and irritation relief: Its hydrating effect calms sensitive areas and reduces discomfort, helping minimize visible redness in early healing.
  • Antioxidant protection: While not a direct antioxidant, it helps buffer oxidative stress, supporting skin clarity in combination with active ingredients.
  • Enhanced topical compatibility: Its lightweight, hydrophilic nature improves the absorption of other cosmetic actives when layered in professional skin care.

These benefits support both immediate comfort and long-term improvements in skin texture, tone, and hydration across cosmetic use cases.

Where Are They Used?

Hyaluronic acid in Ascellos™ is applied topically in cosmetic regimens to restore hydration, ease sensitivity, and improve surface comfort following non-invasive procedures.

  • Post-procedure calming: Used after microneedling, fractional treatments, or peels to reduce redness and improve comfort during recovery.
  • Moisture recovery for dry zones: Helps rehydrate areas of flaking or tightness without adding weight or occlusion.
  • Under-eye dryness relief: Targets delicate skin beneath the eyes to ease dryness, puffiness, and surface fatigue.
  • Blotchiness and redness protocols: Applied in regimens designed to soothe reactivity and support tone balance in stressed skin.
  • Combination with resurfacing actives: Enhances the comfort of exfoliation-based treatments by layering moisture and regenerative factors.

These benefits support both immediate comfort and long-term improvements in skin texture, tone, and hydration across cosmetic use cases.aAll Hyaluronic acid applications in Ascellos™ comply with FDA cosmetic regulations and involve only topical, acellular application with no live cells or systemic absorption.

What are the Considerations?

Hyaluronic acid in Ascellos™ is formulated for cosmetic hydration support using a non-animal, acellular format with no systemic or therapeutic application.

  • Topical cosmetic role: It is used solely in surface-level skincare, with no injectable or drug-based functions.
  • Fermentation-derived sourcing: Produced through microbial biosynthesis to create a vegan, high-purity form suitable for sensitive skin.
  • Formulation integrity: Maintains consistent texture and hydration function without oxidizing or degrading under normal storage.
  • Non-sensitizing profile: Well-tolerated across skin types, making it compatible with post-treatment protocols.
  • Synergy with other actives: Blends smoothly with other Ascellos™ ingredients to support comfort and hydration without disrupting matrix signaling.

These specifications help preserve safety, stability, and performance in cosmetic regimens focused on moisture recovery and skin texture improvement.

Hyaluronic acid in Ascellos™ delivers concentrated hydration through a stable, acellular format designed for topical cosmetic use. It binds water at the skin surface to restore suppleness, ease post-treatment dryness, and support visible smoothness without altering skin structure. This ingredient enhances comfort and compatibility across cosmetic regimens focused on moisture recovery and skin feel.

Resources

Walker, K., Basehore, B. M., Goyal, A., & others. (2023, July 3). Hyaluronic acid. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK482440/

Bravo, B., Correia, P., Gonçalves Junior, J. E., Sant’Anna, B., & Kerob, D. (2022). Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence. Dermatologic Therapy, 35(12), e15903. https://doi.org/10.1111/dth.15903