Collagen V
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Reinforce Skin Structure and Hair Support with Collagen V
Ascellos Collagen V plays a critical role in organizing and regulating the formation of collagen fibrils, especially Collagen I and III. Though less abundant, Collagen V is essential for building healthy skin, strengthening hair structure, and ensuring smooth tissue regeneration.
What Is Type V Collagen?
Collagen V is found in the dermal-epidermal junction of skin, hair follicles, the cornea, and placenta. It helps form the core structure around which other collagens organize. Without sufficient Collagen V, collagen fibrils lose their alignment, leading to weaker skin and tissue repair. It also influences hair strand strength and anchoring within the scalp.
How Does It Work?
Collagen V contributes to the initial stages of fibril assembly, In skin treatments, it supports a more organized and resilient matrix. In hair applications, it strengthens follicle integrity and may help reduce shedding.
- Matrix organization: Guides alignment of collagen I and III for stronger tissue formation.
- Hair anchoring: Supports dermal papilla and follicle stability.
- Skin barrier: Reinforces cellular adhesion for smoother texture and better hydration retention.
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What Are the Benefits?
- Improved skin texture and resilience
- Stronger, healthier-looking hair
- Better dermal regeneration in cosmetic treatments
- Enhanced skin barrier function
Where Is It Used?
- Aesthetics: Facial rejuvenation, microneedling, and post-laser recovery.
- Hair restoration: Scalp health and hair retention in regenerative protocols.
- Skin repair: Wound support and post-inflammatory healing processes.
These effects contribute to post-procedure hydration, recovery, and overall improvement in skin texture using a safe, topical cosmetic format.
What Are the Considerations?
- Allergen sources: Most collagen V comes from bovine or marine sources.
- Not a primary structural collagen: Works best when paired with other collagen types for synergistic results.
- Patient skin type: Sensitivity testing may be useful in individuals with reactive or atopic skin.
- Consistency: Visible improvements usually occur after several weeks of regular use.
Resources
- Birk, D. E. (2001). Type V collagen: heterotypic type I/V collagen interactions in the regulation of fibril assembly. Micron, 32(3), 223–237. https://doi.org/10.1016/S0968-4328(00)00043-3
- Mak, K. M., Png, C. Y. M., & Lee, D. J. (2016). Type V Collagen in Health, Disease, and Fibrosis. Anatomical Record, 299(5), 613–629. https://doi.org/10.1002/ar.23330
