Collagen II

Restore Joint Comfort and Cartilage Health with Collagen II

Ascellos Collagen II is designed to support cartilage structure in joints and help modulate inflammation in both orthopedic and aesthetic applications. While it is primarily known for joint support, its unique anti-inflammatory properties make it valuable in skin-focused regenerative protocols as well.

What Is Type II Collagen?

Collagen II is the primary structural protein found in articular cartilage, responsible for cushioning joints and maintaining smooth movement. It also plays a regulatory role in inflammation, making it a supportive option in skin-focused treatments that aim to reduce redness, irritation, or inflammatory markers associated with skin aging and damage.

How Does It Work?

In orthopedic settings, Collagen II supports chondrocyte activity and helps preserve cartilage by reinforcing its structure and slowing down enzymatic degradation. In aesthetics, Collagen II contributes to a calmer skin environment by helping modulate the inflammatory cascade that contributes to visible aging, irritation, or poor skin texture.

  • Joint support: Reinforces cartilage and helps maintain shock absorption in load-bearing joints.
  • Inflammation control: Modulates localized inflammation in joints and can be used in skin protocols to reduce inflammatory triggers.
  • Skin-calming support: May help balance skin affected by stress, post-procedure redness, or chronic irritation.

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What Are the Benefits?

  • Helps reduce inflammation in skin and joints
  • Supports recovery in post-procedure skin care
  • May aid in calming redness and improving overall tone
  • Maintains joint flexibility and cushioning
  • Contributes to tissue resilience in multi-modal regenerative care

Where Is It Used?

  • Aesthetics: In topical or injectable skin protocols to support calm, healthy tissue post-treatment
  • Combination skin therapies: Used with PRP, exosomes, or microneedling for added anti-inflammatory effects
  • Orthopedics: Still useful in knees, hips, and shoulders to support cartilage structure
  • Sports medicine: For inflammation control in active patients

These effects contribute to post-procedure hydration, recovery, and overall improvement in skin texture using a safe, topical cosmetic format.

What Are the Considerations?

  • Source matters: Most Collagen II is derived from chicken sternum; screen for allergies
  • Treatment planning: Ideal when inflammation is part of the clinical picture, whether in joints or skin
  • Results take time: Effects are gradual and build over 8–12 weeks with consistent use
  • Provider input recommended: Always consult a practitioner when combining with other biologics or in autoimmune conditions

Resources

  • Maynes, R. (Ed.). (2012). Structure and function of Collagen types. Academic Press.