Collagen I

Support Skin and Tissue from the Inside Out with Collagen I

Ascellos Collagen I provides essential structural support for skin, tendons, ligaments, and bones. As our bodies age, collagen I production naturally declines, leading to loss of elasticity, slower healing, and visible signs of aging. Ascellos Collagen I helps reverse these effects by reinforcing the tissue matrix at a cellular level.

What Is Collagen I?

Type I Collagen is the most abundant collagen in the human body, it makes up approximately 25–35% of total protein content. It forms strong fibrils that support connective tissue structure and integrity. In skin care and orthopedic treatments, replenishing collagen I is key to restoring firmness, resilience, and healthy repair.

How Does It Work?

When applied topically or via regenerative therapies, Collagen I stimulates fibroblasts to rebuild the extracellular matrix. These specialized cells ramp up production of new collagen, elastin, and other structural proteins. The result: improved tissue strength, elasticity, and visible smoothing of fine lines.

  • Skin rejuvenation: Enhances collagen regeneration post-procedure (e.g. microneedling, PRP), refining texture and tone.
  • Wound healing & scar care: Provides scaffolding that supports faster, more orderly tissue repair.
  • Orthopedics & soft tissue repair: Strengthens tendons and ligaments by boosting mechanical resilience.

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What Are the Benefits?

  • Improved skin firmness and elasticity — a smoother, more youthful appearance
  • Reduction in fine lines and firmness restoration — especially after aesthetic procedures
  • Support for musculoskeletal tissue — aiding recovery in tendons, ligaments, and connective tissue
  • Accelerated tissue repair — helps wounds heal stronger and with less superficial scarring

Where Is It Used?

  • Aesthetic treatments: As a boost in microneedling, laser, or other collagen induction procedures.
  • Scar management & wound care: In topical or intradermal protocols to rebuild organized tissue structure.
  • Orthopedic applications: Managing tendon or ligament injuries as part of a regenerative care plan.

What Are the Considerations?

  • Consistency matters: Collagen benefits build gradually and require regular application or treatment.
  • Allergen sensitivity: Not advised for patients with known sensitivity to collagen sources, such as bovine, porcine, or marine.
  • Contraindications: Patients with autoimmune conditions, immunocompromised status, or those who are pregnant or breastfeeding should consult a provider before use.
  • Clinical integration: Best used as part of comprehensive regenerative protocols (e.g. exosomes, PRP, microneedling) for synergistic effects.

Resources

  • Amirrah, I. N., Lokanathan, Y., Zulkiflee, I., Wee, M. F. M. R., Motta, A., & Fauzi, M. B. (2022). A comprehensive review on collagen type I development of biomaterials for tissue engineering: From biosynthesis to bioscaffold. Biomedicines, 10(9), 2307. https://doi.org/10.3390/biomedicines10092307