Amniotic Fluid
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A Biocompatible Solution for Skin Recovery
Amniotic fluid is a nutrient-rich substance derived from screened birth tissue and processed into a non-cellular format for cosmetic use in Ascellos™. It contains growth factors, cytokines, hyaluronic acid, and proteins that contribute to visible hydration, tissue support, and surface repair. When applied topically, it helps improve post-procedure outcomes by supporting skin comfort, structure, and moisture balance.

What Is Amniotic Fluid?
Amniotic fluid is a perinatal substance collected during full-term birth that contains hyaluronic acid, cytokines, and growth-related proteins. In topical cosmetic use, it serves as a matrix-rich ingredient that supports hydration, tissue comfort, and surface-level balance. Ascellos™ uses a purified, non-cellular version of amniotic fluid that meets cosmetic standards and contains no live cells or therapeutic agents.
How Does Amniotic Fluid Work?
Amniotic fluid supports post-procedural skin recovery through topical delivery of structural proteins, growth factors, and hydration molecules in a non-cellular cosmetic format.
- Fibroblast and keratinocyte activation: Growth factors and cytokines stimulate skin-repairing cells, helping drive collagen production and visible surface renewal.
- Hydration balance restoration: Hyaluronic acid attracts and retains moisture at the skin surface, improving softness, elasticity, and comfort.
- Collagen support: Structural proteins reinforce the dermal matrix, contributing to post-treatment firmness and recovery.
- Inflammation modulation: Anti-inflammatory molecules calm irritation, helping reduce redness and support a balanced healing response.
- Epithelial repair signaling: Bioactive peptides promote smoother texture and surface integrity by guiding the repair of damaged or stressed skin layers.
These combined effects contribute to post-procedural skin normalization by guiding hydration, structural support, and recovery within a cosmetic framework.
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What are the Benefits of Amniotic Fluid?
Amniotic fluid promotes skin renewal by hydrating the surface, easing irritation, and activating molecular pathways that guide recovery and texture improvement.
- Promotes hydration and skin comfort: Its natural hyaluronic acid content helps retain moisture in the epidermis, improving suppleness without clogging or heaviness.
- Reduces inflammation and surface stress: Cytokines in the fluid help regulate inflammatory responses, making it suitable for post-procedure care or sensitive skin use.
- Stimulates collagen and dermal renewal: Amniotic fluid delivers growth factors that encourage collagen synthesis, aiding visible firmness and wrinkle reduction.
- Improves tone and surface clarity: Pigment-regulating signals help reduce unevenness and contribute to a more radiant, balanced complexion.
- Smooths rough texture and dullness: Matrix proteins help support evenness by guiding tissue repair in areas of prior dryness, stress, or cosmetic damage.
- Supports skin vitality during regeneration: Its bioactive content aids in cellular turnover and supports a fresher, more resilient skin appearance over time.
These benefits position amniotic fluid as a multi-functional skin recovery ingredient for post-procedural support and overall cosmetic revitalization.
What Is Amniotic Fluid Used For?
Amniotic fluid in Ascellos™ is applied topically to promote hydration, soothe inflammation, and improve recovery outcomes following aesthetic skin procedures.
- Redness-prone recovery care: It helps calm irritation and reduce visible flushing after resurfacing or exfoliating procedures.
- Moisture renewal in dry zones: Used in facial areas prone to tightness or flaking, especially following chemical or mechanical treatments.
- Post-peel hydration support: Applied after light or moderate chemical peels to replenish moisture and improve tactile softness.
- Texture refinement in dull skin: Included in regimens aimed at smoothing rough patches and supporting gentle regeneration.
- Radiance enhancement in maintenance care: Used between procedures to support tone balance, surface resilience, and a healthier skin appearance.
All Amniotic fluid applications in Ascellos™ comply with FDA cosmetic standards and are for topical, non-injectable use only, containing no live cells or therapeutic claims.


What Are The Considerations?
Amniotic fluid in Ascellos™ is a purified, non-cellular ingredient derived from full-term births and processed specifically for topical cosmetic use.
- Regulatory use only: It is formulated and applied in accordance with FDA guidelines for non-injectable cosmetic products.
- Screened donor sourcing: Fluid is collected from consenting, medically screened full-term donors during scheduled birth procedures.
- Non-cellular formulation: No live cells or stem cells are included; only extracellular proteins, hydration factors, and soluble bioactives remain.
- Processing and preservation: The material is filtered, stabilized, and stored under controlled conditions to maintain cosmetic quality.
- Application boundaries: It is not intended for systemic delivery, disease treatment, or use outside cosmetic recovery and maintenance protocols.
These practices support responsible use of amniotic fluid as a stable, compliant topical in professional aesthetic regimens.
Amniotic fluid in Ascellos™ provides a topical solution that supports skin hydration, recovery, and visible renewal. Its gentle, acellular format allows providers to use it safely in routine or post-procedural skin care. This ingredient aligns with cosmetic goals by improving comfort, surface quality, and hydration without introducing live cells or drugs.
Resources
Fitzsimmons, E. D., & Bajaj, T. (2023, July 17). Embryology, amniotic fluid. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK541089/
Wgealla, M. M. A. M. A., Liang, H., Chen, R., Xie, Y., Li, F., Qin, M., & Zhang, X. (2022). Amniotic fluid derived stem cells promote skin regeneration and alleviate scar formation through exosomal miRNA-146a-5p via targeting CXCR4. Journal of Cosmetic Dermatology, 21(10), 5026–5036. https://doi.org/10.1111/jocd.14956